- Promotes cardiovascular and bone health
- Only 10,000 ppm material on the market
- Meets pharmaceutical Drug Master File stability requirements
- Addresses the Calcium Paradox
- Pharmaceutical grade Vitamin K2-7
- Stablility verified in finished products
- Each lot tested & verified by a 3rd party laboratory with expertise in Vitamin K2
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Advantage bone, Advantage heart -
Natural Vitamin K2-7
Vitamin K2-7 from Novel is the gold standard in bone and cardiovascular support.
To meet the demanding needs of the industry, it was important to offer the most stable Vitamin K2-7 in the market. Novel’s Vitamin K2-7 retains it’s efficacy in finished products while other brands have been know to become unstable over time.
Strict quality standards allow Novel’s Vitamin K2-7 to meet pharmaceutical Drug Master File publishing requirements and raise it above the rest. Novel’s Vitamin K2-7 is supported by years of stability research and each batch is tested by an independent 3rd party laboratory renowned for their leading research into the benefits of
Vitamin K.
Novel raises the bar in available potencies with an exclusive 10,000 ppm material that is ideal for multivitamins and space conscious formulations.
Premium Quality, Premium Advantage
- Menaquinone-7 (MK-7) form of K2 shown to be most advantageous in bone and cardiovascular health
- 10,000 ppm provides a smaller footprint in multi-ingredient formulations
- Vitamin K2 is much more effective in helping inhibit bone loss than K15
- Longer half life of 72 hours vs. 1 hour for Vitamin K1
- K2 has a better absorption rate of 90% vs. only 10% for Vitamin K1
- 100% Vegetarian
- Naturally sourced from natto, not a synthetic Vitamin K
- Produced at an internationally recognized pharmaceutical facility
- Manufactured under strict pharmaceutical GMPs and regulations
Vitamin K2-7 from Novel is the gold standard
- Vitamin K consumption helps inhibit arterial calcification
- Vitamin K2 MK-7 promotes the synthesis of proteins involved with calcium utilization
- Plays a role in the activation of matrix GLA proteins (MGP)
- Vitamin K2 (MK-7) intake directly linked to healthy bone status
- Low Vitamin K levels are associated with increased risk of fractures
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Improving Bone and Heart Health by Solving the Calcium Paradox
While calcium is a well established supplement for healthy bones, much of the calcium is misdirected into the arteries, increasing vascular calcium levels and in turn, increasing plaque buildup. Vitamin K2 MK-7 breaks this Calcium Paradox by activating Vitamin K dependant proteins involved in blood coagulation, bone metabolism, and the inhibition of arterial calcification.
The carboxylation of the protein Osteocalcin binds the misdirected calcium back to the bone and out of the arteries as Vitamin K activates matrix GLA proteins (MGP) to inhibit calcification of soft tissues.
The Rotterdam study of 4,500 subjects demonstrated that higher levels of MK-7 intake resulted in a lower incidence of aortic calcification. Research has also shown that menaquinone (K2) is more active than K1 in both bone formation and the reduction of bone loss, with one study finding a significant inverse correlation between serum concentrations of MK-7 and the incidence of fractures. Another study of 72,327 women demonstrated Vitamin K intake was inversely related to hip fractures, with a 30% decrease in fractures at the higher intake levels.
Recommended Daily Dosage 45-90 mcg daily
- Kaneki M, Hedges SJ, Hosoi t, Fujiware S. Lyons A, Crean SJ, Ishida N, et al. Japanese fermented soybean food as the major determinant of the large geographical difference in circulating levels of vitamin K2: possible implications for hip-fracture risk. Nutrition 2001 Apr; 17(4)315-21
- Feskanish D, Webber P, Willet WC et al. Vitamin K intake and hip fractures in women: a prospective study. AM J Clin Nutr. 1999; 69:74-9
- The Rotterdam Study, Spronk et al. (J. Vasc Res, in press) Vitamin K2 protects against calcification
- Plaza S.M., Lamson D.W. 2005 Vitamin K2 in Bone Metabolism and Osteoporosis and arterial calcification. Alt Med. Rev. Vol.10, No.1:p24-35
- Vermeer S., et al. Beyond Deficiency: Potential benefits of increased intakes of Vitamin K for bone and vascular health. Eur J Nutr Metab care 2003; 3:433-438z
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Call your sales rep today to hear more about this exciting ingredient.
NJ 866.668.3550 CA 877.327.6662
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*These statements have not been evaluated by the Food and Drug Administration.
This product is not intended to diagnose, treat, cure or prevent any disease.
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